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US 7,125,957 B1Granted
VPR mutant protein and its encoding gene having apoptosis-inducing action
AssigneeRiken
InventorsYoko Aida, Masakazu Kamata
Life of this patent
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Abstract
An apoptosis inducing agent which comprises a protein as being Vpr protein encoded by vpr gene of HIV-1 wherein 15 amino acid residues from the C-terminal are deleted, and an apoptosis inducing gene encoding said protein. The agent induces apoptosis of cells and therefore useful as a medicament for treatment of a cancer or AIDS.
Claims5
An apoptosis inducing agent which comprises an isolated Vpr protein encoded by Vpr gene of HIV-1 wherein 15 amino acid residues from the C-terminal are deleted.
Dependencies are inferred from the claim text.