Methods, compounds, and diagnostics for cancer treatment
AssigneeUnitech Pharmaceuticals, Inc.
InventorsJiajiu Shaw, An-Rong Lee, Wen-Hsin Huang
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Abstract
Methods of treating cancer employing isoxazole derivatives are described. Compounds and methods of using these compounds for isolating and/or detecting binding proteins, which may be indicative of a disease, are also described.
Claims5
A method for the treatment of colon cancer, lung cancer, leukemia, Kaposi's sarcoma, ovarian cancer, sarcoma, meningioma, intestinal cancer, cancer of the lymph nodes, brain tumors, breast cancer, stomach cancer, cancer of the pancreas, cancer of the prostate, and skin cancer comprising administering to a patient or an animal in need thereof a therapeutically effective amount of a compound having a formula (I):
- or a physiologically tolerable salt thereof;
- wherein R is selected from the group consisting of —H, 2-Cl, 3-Cl, 4-Cl, 2,4-(Cl)2, 2-F, 3-F, 4-F, 2,4-(F)2, 2-Br, 3-Br, 4-Br, 2,4-(Br)2, 2-CF3, 3-CF3, 4-CF3, 2,4-(CF3)2, 2-COOH, 3-COOH, 4-COOH, 2,4-(COOH)2, 2-OCH3, 3-OCH3, 4-OCH3, 3,4,5-(OCH3)3, 2-NH—CO—CH2Cl, 4-NH—CO—CH2Cl, 2-NH—CO—CH2Br, 4-NH—CO—CH2Br, or —CONHCH(COOC2H5)CH2CH2COOC2H5.
Dependencies are inferred from the claim text.