Combined therapies for atherosclerosis treatment
AssigneeVasogen Ireland Limited
InventorDavid Elsley
Life of this patent
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Abstract
There is provided a combination treatment for slowing or arresting the progression and/or effecting the regression of atherosclerotic plaque deposits in a mammalian patient, said combination treatment including the administration to the patient of a cholesterol lowering drug such as a statin, and the administration to the patient of an aliquot of a patient's own blood which has been treated ex vivo with one or more stressors selected from an oxidative environment, thermal stress and UV light.
Claims22
In a method for treating atherosclerosis in a mammalian patient with a statin drug wherein the improvement comprises administering to the patient an aliquot of the patient's blood that has been treated ex vivo with one or more stressors, selected from the group consisting of oxidative stress, thermal stress, and UV light.
A method of slowing or arresting the progression and/or effecting the regression of atherosclerotic plaque deposits and/or improving the stability of such plaques in a mammalian patient, the method comprising administering to the patient a statin drug and an aliquot of the patient's own blood which has been treated ex vivo with one or more stressors, selected from the group consisting of an oxidative stress, thermal stress, and UV light.
A method of reducing serum lipid levels and/or combating the development of atherosclerosis in a mammalian patient, the method comprising:
- a) administering to the patient an aliquot of the patients own blood which has been treated ex vivo with one or more stressors, selected from the group consisting of, an oxidative stress, thermal stress, and UV light;
- and
- b) administering to the patient a statin drug.
A method of enhancing the reduction in serum lipid levels in a mammalian patient caused by administration of a statin drug, the method comprising:
- a) administering to the patient an aliquot of the patient's own blood which has been treated ex vivo with one or more stressors, selected from the group consisting of an oxidative stress, thermal stress, and UV light;
- and
- b) administering to the patient a statin drug.
Dependencies are inferred from the claim text.