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US 7,125,886 B2Granted
5-HT3 receptor antagonists and methods of use
AssigneeARYx Therapeutics, Inc.
InventorsXiaoming Zhang, Jurg R. Pfister, Cyrus Becker, Pascal Druzgala
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Abstract
The subject invention provides useful and novel 5-HT3 antagonists. The subject invention also provides methods for synthesizing the compounds of invention. The invention also provides methods for the treatment of irritable bowel syndrome and other such conditions.
Claims12
The compound, wherein said compound has the following structure, or a salt of a compound having the following structure:
- wherein,
- X=N or CH;
- and
- R=lower alkyl substituted with OH or NH2.
1 more element
The pharmaceutical composition, comprising a compound, or salt thereof, wherein said compound has the following structure:
- wherein
- X=N or CH;
- and
- R=lower alkyl substituted with OH or NH2.
1 more element
Dependencies are inferred from the claim text.