Thienothiazine compound having anti-inflammatory and analgesic properties and method of making and using the same
OwnerJing Liinventor
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Abstract
The present invention is related to a type of thienothiazine compounds having molecular structure of formula (1) and their pharmaceutically acceptable salts or solvates. The present invention is also related to the method of producing the formula (1) compound, an anti-inflammatory and analgesic pharmaceutical composition containing the formula (1) compound, and the method of using the formula (1) compound to prepare anti-inflammatory and analgesic medicine
Claims10
A thieno-[2,3-e]-1,2-thiazine compound having a structure of formula (1) and pharmaceutical acceptable salts or solvates thereof:
- wherein R1 is methyl, ethyl, propyl, isopropyl or butyl;
- R2 is methyl, ethyl, propyl, isopropyl or butyl;
- and X is F, Cl, Br, OCH3 or OH.
A method of producing a formula (1) compound comprising reacting a formula (2) compound with a formula (3) compound,
- wherein R1 is methyl, ethyl, propyl, isopropyl or butyl;
- R2 is methyl, ethyl, propyl, isopropyl or butyl;
- and X is F, Cl, Br. OCH3 or OH.
A pharmaceutical composition comprising:
- (a) a formula (1) compound as active component,
- wherein R1 is methyl, ethyl, propyl, isopropyl or butyl;
- R2 is methyl, ethyl, propyl, isopropyl or butyl;
- and X is F, Cl, Br, OCH3 or OH;
- and
- (b) a pharmaceutical auxiliary or carrier.
A method of making an anti-inflammatory and analgesic medicine comprising:
- (a) providing a compound defined by formula (1),
- wherein R1 is methyl, ethyl, propyl, isopropyl or butyl;
- R2 is methyl, ethyl, propyl, isopropyl or butyl;
- and X is F, Cl, Br, OCH3 or and
- (b) mixing said compound with a pharmaceutical auxiliary or carrier to produce said medicine.
Dependencies are inferred from the claim text.