Human mullerian duct-derived epithelial cells and methods of isolation and uses thereof
AssigneeRaven Biotechnologies, Inc.
InventorsRong-hao Li, Jennie Powell Mather
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Abstract
This invention discloses a substantially pure population of human Müllerian duct-derived epithelial cells and methods of isolating and culturing the Müllerian duct-derived epithelial cells. By carefully manipulating the microenvironment in which the Müllerian duct-derived epithelial cells are grown, multiple passages are attainable wherein the Müllerian duct-derived epithelial cells are capable of becoming uterine, cervical, vaginal, and oviductal cells. In addition, several uses of human Müllerian duct-derived epithelial cells and cells differentiating therefrom are disclosed herein.
Claims4
A method of providing a source of an immunogen to a heterologous recipient, comprising:
- administering to said recipient a substantially pure population of human Müllerian duct-derived epithelial cells in an amount effective to induce an immune response in said recipient;
- wherein said Müllerian duct-derived epithelial cells have a pluripotent capacity to differentiate into uterine, oviductal, cervical, and vaginal cells.
Dependencies are inferred from the claim text.