US 7,125,700 B2 · Cyclic GMP dependent protein kinase as a chemotherapeutic target for antiprotozoal agents

Abstract

Protozoal cyclic GMP dependent protein kinases have been isolated and cloned. These enzymes may be used in screening assays to identify potential antiprotozoal agents.

Claims1

Dependent claims

A substantially pure cGMP dependent protein kinase polypeptide comprising the amino acid sequence encoded by the nucleotide sequence set forth in SEQ ID NO:10.

Dependencies are inferred from the claim text.

Facts

Application

10/348,155Filed 21 Jan 2003 · division

Priority

13 Apr 1999

Published

US 2003/0211552 A113 Nov 2003

Granted

24 Oct 2006

Term ends

Not estimatedThe source records don’t support an estimate.

Classification7 codes

C12N 9/1205
Transferring phosphorus containing groups, e.g. kinases: phosphotransferases with an alcohol group as acceptor , e.g. protein kinases
C12Q 1/18
Involving viable microorganisms: testing for antimicrobial activity of a material
C12Q 1/485
Involving transferase: involving kinase
G01N 2333/45
From protozoa: toxoplasma

Family

Application60/129,058Us provisional application · filed 13 Apr 1999

Application09/521,511Parent of this division · filed 8 Mar 2000

US 2003/0211552 A1Pre-grant publication · published 13 Nov 2003

US 6,555,358 B1Parent of this division

US 7,125,700 B2This patent

From the US filing history. Foreign family members aren’t listed.

Abstract

Protozoal cyclic GMP dependent protein kinases have been isolated and cloned. These enzymes may be used in screening assays to identify potential antiprotozoal agents.

Cyclic GMP dependent protein kinase as a chemotherapeutic target for antiprotozoal agents

Life of this patent

Abstract

Claims1

Cyclic GMP dependent protein kinase as a chemotherapeutic target for antiprotozoal agents

Life of this patent

Abstract

Claims1