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US 7,125,684 B2Granted
Human mater proteins
AssigneeSchering Corporation
InventorsBertram Weiss, Monika Lessl, Michaele Peters-Kottig, Georg Beckmann
Life of this patent
Estimating the term…
Abstract
Two human MATER proteins as well as their use for fertility disorders, therapy and diagnosis are described.
Claims9
A method for the identification of an effector of a polypeptide, comprising:
- contacting (a) (1) a polypeptide encoded by a nucleotide sequence that hybridizes to the complete complement of SEQ ID NO:1 or 3 under stringent hybridization conditions comprising washing for 1 hour at 68° C. with 1×SSC and 0.1% SDS and which polypeptide possesses nucleoside triphosphatase (NTPase) activity, or (2) a polypeptide fragment of said (1) polypeptide which retains NTPase activity,
- with (b) a test effector, and measuring the NTPase activity of said polypeptide.
A method for the identification of an effector of a polypeptide, comprising:
- contacting (a) a polypeptide of SEQ ID NO:
- 2 or 4, with (b) a test effector, and measuring the NTPase activity of said polypeptide.
Dependencies are inferred from the claim text.