Sequences for the detection of Escherichia coli
AssigneeThe University of Sydney
InventorsPeter Richard Reeves, Lei Wang
Life of this patent
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Abstract
An isolated nucleic acid molecule comprising a nucleotide sequence encoding a transcriptional enhancer of cytochrome P450 (P450) CYP3A4 production or expression is disclosed, as are uses of the nucleic acid molecule for screening compounds for xenobiotic induction of CYP3A4 expression in cells and animals.
Claims24
An isolated and purified nucleic acid molecule consisting of a fragment of SEQ ID NO:
- 13, wherein said fragment comprises 10 or more nucleotides of the nucleotide sequence from position 586 to position 810 of SEQ ID NO:
- 13.
A composition consisting essentially of an isolated and purified nucleic acid molecule consisting of a fragment of SEQ ID NO:
- 13, wherein said fragment comprises 10 or more nucleotides of the nucleotide sequence from position 586 to position 810 of SEQ ID NO:
- 13.
An isolated and purified nucleic acid molecule primer consisting of a fragment of SEQ ID NO:
- 13, wherein said fragment consists of 10 to about 20 nucleotides of the nucleotide sequence from position 586 to position 810 of SEQ ID NO:
- 13.
An isolated and purified nucleic acid consisting of 10 or more nucleotides of SEQ ID NO:
- 13.
An isolated and purified nucleic acid consisting of 20 or more nucleotides of SEQ ID NO:
- 13.
Dependencies are inferred from the claim text.