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US 7,119,202 B1Granted
Substituted-1,3-oxathiolanes and substituted-1,3-dioxolanes with antiviral properties
AssigneeGlaxo Wellcome Inc.
InventorPaul Nguyen Ba
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Abstract
Disclosed are compounds of the formula wherein R1 is hydrogen or an acyl group having 1 to 16 carbon atoms; R2 is a purine or pyrimidine base or an analogue or derivative thereof; Z is O, S, S═O or SO2; and pharmaceutically acceptable derivatives thereof. Also described are processes for and intermediates of use in their preparation, pharmaceutical compositions containing these compounds, and the use of these compounds in the antiviral treatment of mammals.
Claims1
Cis-2-hydroxymethyl-5-(cytosin-1′-yl)-1,3-oxathiolane substantially in the form of a single enantiomer or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.