RelA-associated inhibitor, process for producing the same and utilization thereof
AssigneeCity of Nagoya
InventorTakashi Okamoto
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Abstract
Human RelA-associated inhibitor (RAI) comprises 351 amino acids and is capable of binding to p65, a subunit of the transcription factor NFκB. A process for producing RAI, a cDNA encoding it, a fragment capable of hybridizing selectively to the cDNA sequence, a plasmid for expression and duplication comprising the cDNA, a host cell transformed with the plasmid, an antibody against the polypeptide, a pharmaceutical composition comprising the polypeptide or the antibody against it and a method for diagnosis of diseases using the antibody against the RAI are disclosed.
Claims1
A substantially pure polypeptide comprising the amino acid sequence represented by SEQ ID NO:1.
Dependencies are inferred from the claim text.