3,3-diphenylpropylamines useful in therapy

A 3,3-diphenylpropylamine of the formula

• and any stereoisomers thereof;
• wherein R1 represents —H or —CH3;
• R2 represents —CX3, —CR2-1X2, —CR2-1R2-2X, or —CR2-1R2-2H, wherein X represents halogen, and R2-1 and R2-2 independently represent —H or —(C1–C4 alkyl), optionally substituted with halogen;
• R3 and R4 independently represent —H, —OCH3, —OH, —CONH2, —SO2NH2, —F, —Cl, —Br, —I, —CF3, or —(C1–C4 alkyl) , optionally substituted with one or two —OH, —(C1–C4 alkoxy), —COOH, or —CO—O—(C1–C3 alkyl);
• and
• R5 and R6 independently represent C1–C6 alkyl, optionally substituted with hydroxyl, wherein R5 and R6 together contain at least three carbon atoms, and wherein R5 and R6 may form a ring together with the amine nitrogen;
• provided that R2 comprises at least one halogen and, further provided, that when R1 is hydrogen, R2 is 5-trifluoromethyl, and R3 and R4 are both hydrogen, then R5 and R6 are not both isopropyl;
• or a physiologically acceptable acid addition salt thereof.