Tocopherol enriched compositions and amelioration of inflammatory symptoms
AssigneeGalileo Pharmaceuticals, Inc.
InventorsPeggy Beinlich, Sekhar Boddupalli, Lesley A. Brown, Darlene M. Dreon, Stephen Flaim, Guy Miller, Stephen D. Phinney
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Abstract
The present invention provides non-alpha-tocopherol enriched tocopherol compositions and non-alpha-tocopherol metabolite enriched compositions for use in the reduction of inflammatory markers associated with inflammation such as C-reactive protein.
Claims17
A method of reducing the level of C-reactive protein (CRP) in an individual subject to a CRP associated inflammatory condition comprising administering to the individual an effective amount of a non-alpha-tocopherol enriched tocopherol composition, wherein said non-alpha tocopherol is selected from the group consisting of gamma-toconherol, beta-tocopherol and delta tocopherol, and wherein said composition comprises less than 30% alpha-toconherol.
A method of reducing the level of C-reactive protein (CRP) in an individual subject to a CRP associated inflammatory condition comprising administering to the individual an effective amount of non-alpha-tocopherol enriched tocopherol composition, wherein said composition comprises at least 60% ganima-tocopherol, at least 28% delta-tocopherol and no greater than 10% alpha-tocopherol.
A method of reducing the level of C-reactive protein (CRP) in an individual subject to a CRP associated inflammatory condition comprising administering to the individual an effective amount of a metabolite of a non-alpha-tocopherol selected from the group consisting of a beta-tocopherol metabolite, a gamma-tocopherol metabolite and a delta-tocopherol metabolite.
Dependencies are inferred from the claim text.