Use of herbal agents for potentiation of bioefficacy of anti infectives

A composition comprising a mixture of an anti-infective agent and a potentiator comprising a 3′,5-dihydroxy flavone 7-O-β-D-galacturonide-4′-O-β-D-glucopyranoside compound of formula 2 in pure form or in the form of a HPLC fingerprinted fraction of 3′,5-dihydroxy flavone 7-O-β-D-galacturonide-4′-O-β-D-glucopyranoside from Cuminum cyminum said potentiator optionally also comprising a piperine compound of formula 1:

• said potentiator being present in the composition in an amount effective to potentiate the effectiveness of the anti-infective agent against a microorganism such that the composition has an increased bioefficacy against the microorganisms than does the composition without the potentiator.