Back to results
US 7,118,863 B2Granted
Methods for detecting NTR3 nucleic acids by hybridization
AssigneeAmgen Inc.
InventorHailing Hsu
Life of this patent
Estimating the term…
Abstract
The present invention provides a purified polynucleotide encoding a novel receptor, designated NTR3, which belongs to the TNF receptor gene superfamily; to purified NTR3 polypeptide molecules; to antibodies that bind NTR3; to materials comprising such molecules; and to methods of using such molecules.
Claims7
A method for determining the presence of an NTR3 nucleic acid in a biological sample comprising the steps of:
- (a) providing a biological sample suspected of containing an NTR3 nucleic acid;
- (b) contacting the biological sample with a diagnostic reagent comprising a detectably labeled nucleic acid comprising a nucleotide sequence selected from the group consisting of(1) the nucleotide sequence set forth in SEQ ID NO:
- 1;
- and (2) a nucleotide sequence fully complementary to (1) wherein the diagnostic reagent will hybridize with an NTR3 nucleic acid in said biological sample;
- and
- (c) determining the presence of an NTR3 nucleic acid in the biological sample by detecting hybridization between an NTR3 nucleic acid in the biological sample and the diagnostic reagent.
3 more elements
A method for detecting the presence of an NTR3 nucleic acid in a tissue or cellular sample comprising the steps of:
- (a) providing a tissue or cellular sample suspected of containing an NTR3 nucleic acid;
- (b) contacting the tissue or cellular sample with a diagnostic reagent comprising a detectably labeled nucleic acid comprising a nucleotide sequence selected from the group consisting of (1) the nucleotide sequence set forth in SEQ ID NO:
- 1;
- and (2) a nucleotide sequence fully complementary to (1) under conditions wherein the diagnostic reagent will hybridize with an NTR3 nucleic acid;
- and
- (c) determining the presence of an NTR3 nucleic acid in the tissue or cellular sample by detecting hybridization between an NTR3 nucleic acid in the tissue or cellular sample and the diagnostic reagent.
3 more elements
Dependencies are inferred from the claim text.