Methods of classifying, diagnosing, stratifying and treating cancer patients and their tumors

A method of providing diagnostic, prognostic, or predictive information for a breast tumor comprising steps of:

• providing a breast tumor sample;
• detecting expression or activity of a gene encoding the polypeptide of SEQ ID NO:3 in the sample;
• classifying the tumor as belonging to a tumor subclass based on the results of the detecting step;
• and
• providing diagnostic, prognostic, or predictive information based on the classifying step.

A method of selecting a treatment for a breast tumor comorising steps of:

• providing a breast tumor sample;
• detecting expression or activity of a gene encoding the polypeptide of SEQ ID NO:3 in the sample;
• classifying the tumor as belonging to a tumor subclass based on the results of the detecting step;
• and
• selecting a treatment based on the classifying step.

A method of providing diagnostic, prognostic, or predictive information about a subject having a breast tumor comprising steps of:

• providing a sample isolated from a subject having a breast tumor;
• detecting expression or activity of a gene encoding the polypeptide of SEQ ID NO:3 in the sample;
• and
• providing diagnostic, prognostic, or predictive information about the subject based on the results of the detecting step.

A method of stratifying a subject having a breast tumor for a clinical trial comprising steps of:

• providing a sample isolated from a subject having a breast tumor;
• detecting expression or activity of a gene encoding the polypeptide of SEQ ID NO:3 in the sample;
• and
• stratifying the subject for a clinical trial based on the results of the detecting step.

A method of selecting a treatment for a subject having a breast tumor comprising steps of:

• providing a sample isolated from a subject having a breast tumor;
• detecting expression or activity of a gene encoding the polypeptide of SEQ ID NO:3 in the sample;
• and
• selecting a treatment based on the results of the detecting step.