Pelletized chromotography media
AssigneePierce Biotechnology, Inc.
InventorConnie A. Draveling
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Abstract
A method of using a pellet composed of an aggregate of distinct beads of a chromatography media. The pellet is coherent and capable of being rapidly hydrated on addition of water to form a gel wherein said beads are swollen and substantially uniformly dispersed in the water phase and a combination of the a ligand with the chromatography media.
Claims9
A pellet of chromatography media of agarose, dextran or acrylamide/azlactone copolymer characterized by a coherent aggregate of distinct beads having a capacity to resist a force, as demonstrated by a Schleuinger Pharmatron hardness of at least about 2 Kilo Ponds, and capable of being rapidly hydrated on addition of water to form a gel where said media has been derivatized with a ligand.
The method of using a pelletized chromatography media of agarose, dextran or acrylamide/azlactone copolymer characterized by a coherent aggregate of distinct beads having a capacity to resist a force, as demonstrated by a Schleuinger Pharmatron hardness of at least about 2 Kilo Ponds, including the step of rapidly hydrating the media to form a gel.
The method of hydrating a pellet consisting essentially of an aggregate of distinct beads of a chromatography media composed of crosslinked agarose, dextran or acrylamide/azlactone where the pellet is coherent and capable of resisting force, as demonstrated by a Schleuinger Pharmatron hardness of at least about 2 Kilo Ponds, including the step of adding water to the pellet which hyrdates within 120 seconds to form a gel wherein said beads are swollen and substantially uniformly dispersed.
Dependencies are inferred from the claim text.