Back to results
US 7,118,758 B1Granted
Transformed bacteria producing CS6 antigens as vaccines
AssigneeThe United States of America as represented by the Secretary of the Army
InventorsMarcia K. Wolf, Fred J. Cassels, Edgar Charles Boedeker
Life of this patent
Estimating the term…
Abstract
Disclosed herein are antigens that stimulate protective antibodies against enterotoxigenic Escherichia coli. Also disclosed herein are proteins encoded by cssA and cssB genes as well as constructs containing the genes and methods of using thereof.
Claims2
A composition for induction of a mucosal immune response comprising an isolated and purified protein containing the sequence
- (SEQ ID NO.10)
- GNWQYKSLDV NVNIEQNFIP DIDSAVRIIP VNYDSDPKLD
- SQLYTVEMTI PAGVSAVKIA PTDSLTSSGQ QIGKLVNVNN
- PDQNMNYYIR KDSGAGNFMA GQKGSFPVKE NTSYTFSAIY
- TGGEYPNSGY SSGTYAGNLT VSFYSN
- in a pharmaceutically acceptable carrier wherein the pharmaceutically acceptable carrier is selected from the group consisting of liposomes, microcrystals, microdroplets, microcapsulated formulations and enterically coated capsules.
3 more elements
Dependencies are inferred from the claim text.