Meningococcal class 1 outer-membrane protein vaccine
AssigneesWyeth Holdings Corporation, De Staat Der Nederlanden Vertegenwoordigd Door de Minister Van Welzijn, Volksgezondheid En Cultuur
InventorsRobert C. Seid, Jr., Peter R. Paradiso, Jan T. Poolman, Peter Hoogerhout, Emmanuel J. H. J. Wiertz, Peter van der Ley, John Edward Heckels, Ian Nicholas Clarke
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Abstract
Outer-membrane vesicles, Class 1 outer membrane proteins of Neisseria meningitidis, fragments or oligopeptides containing epitopes of the Class I OMP can be used to immunize against meningococcal disease.
Claims9
A vaccine comprising purified Neisseria meningitidis Class 1 outer-membrane proteins of more than one subtype, in a pharmaceutically acceptable vehicle.
A vaccine comprising purified meningococcal Class 1 outer-membrane proteins of more than one subtype, in a pharmaceutically acceptable vehicle, wherein the vaccine elicits antibodies against said meningococcal Class 1 outer-membrane proteins in a mammal.
An antigenic composition comprising a conjugate of a surface loop peptide of Neisseria meningitidis Class 1 outer-membrane protein linked to a carrier protein.
Dependencies are inferred from the claim text.