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US 7,118,756 B2Granted
Recombinant protective protein from Streptococcus pneumoniae
AssigneeWyeth
InventorsBruce A. Green, Amy W. Masi
Life of this patent
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Abstract
The present invention discloses amino acid sequences and nucleic acid sequences relating to a Streptococcus Pneumoniae surface associated Pneumo Protective Protein (PPP) having a molecular weight of about 20 kilo Daltons (kDa). The PPP exhibits the ability to reduce colonization of pneumococcal bacteria. Thus the present invention also pertains to compositions for the treatment and prophylaxis of infection or inflammation associated with bacterial infection.
Claims9
An immunogenic composition comprising an isolated Streptococcus pneumoniae Pneumo Protective Protein (PPP) comprising the amino acid sequence of SEQ ID NO:
- 5, wherein the PPP has a molecular weight of about 20 kDa and the ability to reduce colonization of pneumococcal bacteria.
Dependencies are inferred from the claim text.