Back to results
US 7,118,753 B2Granted
Enhancing cell-based immunotherapy
AssigneeAnawrahta Biotech Co., Ltd.
InventorsShih-Jen Liu, Wei-Yu Lo
Life of this patent
Estimating the term…
Abstract
An immunogenic composition containing antigen-presenting cells and a heat shock protein or a heat shock fusion protein. Also disclosed is a method of using such a composition for enhancing cell-based immunotherapy, especially cancer immunotherapy. The method includes administering the composition to a target site.
Claims12
An immunogenic composition comprising
- (i) antigen-presenting cells;
- (ii) a purified fragment of human Hsp 70, consisting essentially of amino acids 480–640 of the human Hsp 70, fused to a human antigen unrelated to a heat shock protein;
- and
- (iii) a pharmaceutically acceptable carrier,
- wherein the composition is free of any human antigen that is not covalently bound to the fragment of human Hsp 70.
2 more elements
Dependencies are inferred from the claim text.