β-Superfamily conotoxins
AssigneesUniversity of Utah Research Foundation, Cognetix, Inc.
InventorsRobert M. Jones, Baldomero M. Olivera, Maren Watkins, James E. Garrett
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Abstract
The present invention is directed to β-superfamily conotoxin peptides, derivatives or pharmaceutically acceptable salts thereof. The present invention is further directed to the use of this peptide, derivatives thereof and pharmaceutically acceptable salts thereof for the treatment of disorders associated with voltage-gated ion channels, ligand gated channels and other receptors. The invention is further directed to nucleic acid sequences encoding the β-superfamily conotoxin peptides and encoding β-superfamily conotoxin propeptides, as well as the β-superfamily conotoxin propeptides.
Claims20
An isolated peptide comprising the amino acid sequence set forth in SEQ ID NO:
- 18.
An isolated β-superfamily conopeptide propeptide comprising the amino acid sequence set forth in SEQ ID NO:
- 17.
Dependencies are inferred from the claim text.