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US 7,115,568 B2Granted
Methods using TCF II
AssigneeDaiichi Pharmaceutical Co., Ltd.
InventorsMasamichi Kojiro, Hirohisa Yano, Akihiro Iemura
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Abstract
The present invention provides an agent for preventing and/or treating cachexia comprising TCF-II as an effective ingredient. An agent for preventing and treating cachexia caused by cancer, acquired immunodeficient syndrome (AIDS), cardiac diseases, infectious disease, shock, burn, endotoxinemia, organ inflammation, surgery, diabetes, collagen diseases, radiotherapy, chemotherapy is provided by the present invention.
Claims4
A method for reducing the TNF-α level in a patient having a cancer comprising the steps of:
- administering Tumor Cytotoxic Factor II to the cancer patient in a dosage between about 0.3 mg/kg body weight/day and about 30 mg/kg body weight/day, and
- determining the level of TNF-α in the patient after the administration of Tumor Cytotoxic Factor II.
Dependencies are inferred from the claim text.