Use of certain drugs for treating nerve root injury
AssigneeSciaticon AB
InventorKjell Olmarker
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Abstract
The present invention relates to a method and a pharmaceutical composition for treatment of nerve disorders comprising administration of a therapeutically effective dosage of at least two substances selected from the group consisting of TNF inhibitors, IL-1 inhibitors, IL-6 inhibitors, IL-8 inhibitors, FAS inhibitors, FAS ligand inhibitors, and IFN-gamma inhibitors. Preferably, at least one of the substances is a TNF inhibitor.
Claims42
A method for treatment of a nerve disorder selected from the group consisting of nerve root injury, sciatica, low back pain, whiplash associated disorder, nucleus pulposus-induced nerve injury, spinal cord compression, cervical rhizopathy, and a nerve disorder caused by a disk herniation in a subject comprising administering to said subject a therapeutically effective dosage of a first TNF inhibitor in combination with a second TNF inhibitor.
A method for treatment of a nerve disorder selected from the group consisting of nerve root injury, sciatica, low back pain, whiplash associated disorder, nucleus pulposus-induced nerve injury, spinal cord compression, cervical rhizopathy, and a nerve disorder caused by a disk herniation in a subject comprising administering to said subject a therapeutically effective dosage of a TNF inhibitor in combination with a IL-1 inhibitor.
Dependencies are inferred from the claim text.