Proteoglycan compositions for the treatment of cardiovascular inflammatory diseases
OwnerTheoharis C Theoharidesinventor
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Abstract
Compositions with synergistic anti-inflammatory effects in inflammatory diseases resulting from activation and consequent degranulation of mast cells and followed by secretion of inflammatory biomolecules from the activated mast cells, composed of a heavily sulfated, non-bovine proteoglycan such as shark cartilage chondroitin sulfate C, and one or more of a hexosamine sulfate such as D-glucosamine sulfate, a flavone such as quercetin, an unrefined kernel olive oil that increases absorption of these compositions in various routes of administration, S-adenosylmethionine, a histamine-1 receptor antagonist, a histamine-3 receptor agonist, an antagonist of the actions of CRH, caffeine, and a polyamine.
Claims2
A composition for oral use with synergistic anti-inflammatory properties in cardiovascular inflammatory conditions induced by the activation of mast cells, and subsequent secretion of vasoactive and inflammatory biomolecules, comprising, in mg soft gel capsule:
- chondroitin sulfate, 25–75;
- rutin, 25–75;
- quercetin, 50–150;
- S-adenosylmethionine, 150–250;
- folio acid, 0.17–0.37;
- fish oil polyunsaturated fatty acids, 150–200;
- microfiltered olive kernel extract, 200–300;
- bitter willow extract, 10–50;
- suspension agents, 50–70.
Dependencies are inferred from the claim text.