Compositions and methods for WT1 specific immunotherapy
AssigneesCorixa Corporation, University of Washington
InventorsAlexander Gaiger, Martin A. Cheever
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Abstract
Compositions and methods for the therapy of malignant diseases, such as leukemia and cancer, are disclosed. The compositions comprise a WT1 polypeptide comprising an immunogenic portion of WT1, wherein said WT1 polypeptide comprises the polypeptide of SEQ ID NO:144. Such compositions may be used, for example, for the prevention and treatment of metastatic diseases.
Claims4
A polypeptide consisting of an immunogenic portion of a native WT1, wherein the polypeptide consists of the polypeptide set forth in SEQ ID NO:144.
A polypeptide, wherein the polypeptide consists of 4–9 consecutive amino acids of SEQ ID NO:144.
A polypeptide, wherein the polypeptide consists of 8–9 consecutive amino acids of SEQ ID NO:144.
Dependencies are inferred from the claim text.