Apparatus and method for monitoring molecular species within a medium
AssigneeAlpha M.O.S.
InventorFrederic Zenhausern
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AssigneeAlpha M.O.S.
InventorFrederic Zenhausern
Estimating the term…
Apparatus and methods for monitoring, analyzing, and/or discriminating molecular species, preferably a biomolecule, within a medium using a multisensor array (MSA) and multivariate processing. Biological compounds such as nucleotides and polynucleotides can be detected and analyzed. A reaction process such as an accumulation cycle of nucleic acids can be monitored, analyzed, and controlled using a multisensor array (MSA) and multivariate processing. Monitoring a biomolecule includes interrogating the medium, and preferably its gas phase, by coupling a sensor responsive to any changes of the medium and or biomolecule and its secondary products when, for example, an amplification reaction is proceeded. It is also a scope of the present invention to use direct detection and monitoring of biomolecular reactions in real-time without radioactive or fluorescent labeling. A preferred application is real-time polymerase chain reaction (PCR) detection.
An apparatus for analyzing at least one unlabelled biomolecule selected from the group consisting of protein, lipid, carbohydrate and nucleic acid, during a reaction process, by monitoring volatile compounds directly in-situ within a gas or vapor phase medium from the reaction, comprising:
An apparatus for controlling a nucleic acid replication process, comprising:
An apparatus for detecting at least one of a bacteria, bacteriophage, or a virus, comprising:
An apparatus for analyzing at least one of a bacteria, a bacteriophage, or a virus, comprising:
Dependencies are inferred from the claim text.