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US 7,115,163 B2Granted
Magnesium ammonium phosphate cement composition
AssigneeKyphon Inc.
InventorMichael Zimmermann
Life of this patent
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Abstract
This invention relates to a cement, which comprises in its main phase of microcrystalline magnesium ammonium phosphate and nanoapatite after hardening and thus at the same time has considerable strength. The material is biologically degradable and is suitable for application in tooth cements, as bone replacement, as bone filler, as bone cement or as bone adhesive.
Claims14
A method of repairing or replacing bone comprising:
- a) combining a powder mixture with a mixing liquid to obtain a cement paste, the powder mixture comprising molar quantities of the components calcium (Ca), magnesium (Mg) and orthophosphate (P) in the mixture in the ranges 1<Ca/P<1.5 and Mg/P<0.5, an amount of strontium to cause the cement paste to expand during hardening, and an ammonium salt;
- and
- b) applying the paste to or into a target zone of a bone.
A composition comprising:
- an ammonium salt;
- and
- a powder mixture comprising molar quantities of the components calcium (Ca), magnesium (Mg) and orthophosphate (P) in a mixture in the ranges 1<Ca/P<1.5 and Mg/P<0.5, the powder mixture further comprising strontium in an amount of weight percent of the composition such that when the powder mixture and the ammonium salt are combined, the ammonium salt and the powder mixture form a magnesium ammonium phosphate cement preparation, wherein the expansivity of the cement preparation is adjusted by the proportion of the strontium added.
Dependencies are inferred from the claim text.