Fused bicyclic amide compounds and medicinal use thereof

A fused bicyclic amide compound represented by the formula (I)

• wherein R1 is hydrogen, alkyl, halogen, hydroxyl group or alkoxy;
• R2 and R3 are the same or different and each is hydrogen, alkyl or halogen;
• ring A is benzene or cyclohexane, represented by one of the following formulas:
• ring B is pyrrole or a derivative thereof, furan or thiophene, represented by one of the following formulas:
• wherein R5 is hydrogen, alkyl, alkoxycarbonylalkyl, hydroxycarbonylalkyl, acyloxyalkyl or hydroxyalkyl;
• W is hydrogen, alkyl or hydroxycarbonylalkyl;
• X is cyano;
• X′ is hydrogen;
• and
• Y is piperidine having at least one substituent selected from the group consisting of hydroxy;
• carboxy;
• alkoxycarbonyl;
• hydroxyalkyl;
• alkoxyalkoxy;
• carboxyalkylcarbonyloxy;
• acyloxy;
• benzoyloxy;
• phenyl;
• alkylenedioxy;
• oxo;
• amino optionally mono- or di- substituted by alkoxyalkyl;
• cyclic amine selected from piperidine optionally having substituent, morpholine, thiomorpholine, and piperazine optionally having substituent (wherein the cyclic amine may be N-oxide);
• and morpholinomethyl;
• or a pharmaceutically acceptable salt thereof.