US 7,098,246 B2Granted

Natural compounds and their derivatives for the prevention and treatment of cardiovascular, hepatic and renal diseases and for cosmetic applications

AssigneePuleva Biotech, S.A.

InventorsArjan Geelings, Eduardo Lopez-Huertas Leon, Juan Carlos Morales Sanchez, Julio Boza Puerta, Jesús Jimenez Lopez

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Abstract

The present invention refers to the use of phenolic compounds and their derivatives represented by formula I wherein R1 and R2 are selected from among: OH, OCOalkyl, or OCOalkenyl, and R3 is either H, OH, OCOalkyl or OCOalkenyl, wherein the alkyl or alkenyl chains present from 2 to 22 carbon atoms and wherein at least one OCOalkyl or OCOalkenyl group is present in the structure, for the prevention and treatment of cardiovascular, hepatic or renal diseases, as well as to their cosmetic applications, to compositions that include these compounds and to some novel phenolic compounds and derivatives.

Claims9

Dependent claims

A phenolic compound selected from the group consisting of 2-(3,4-dihydroxyphenyl) ethyl stearate (IV),

2-(3,4-dihydroxyphenyl) ethyl oleate (V)
2-(3-stearyloxy-4-hydroxyphenyl) ethanol (VI),
2-(4-stearyloxy-3-hydroxyphenyl) ethanol (VII),
2-(3,4-distearyloxyphenyl) ethyl stearate (IX),
2-(3,4-dioleyloxyphneyl) ethyl oleate (X),
2-(3,4-dihydroxyphenyl) ethyl eicosapentanoate (XI),
2-(3,4-dihydroxyphenyl) ethyl docosahexanoate (XII),
2-(3,4-dieicosapentanoyloxyphenyl) ethyl eicosapentanoate (XIII),
2-(3,4-didocosahexanoyloxyphenyl) ethyl docosahexanoate (XIV),
2-(4-hydroxyphenyl) ethyl eicosapentanoate (XIX),
2-(4-hydroxyphenyl) ethyl docosahexanoate (XX),
2-(4-stearyloxyphenyl) ethyl stearate (XXII),
2-(4-oleyloxyphenyl) ethyl oleate (XXIII),
2-(4-eicosapentanoyloxyphenyl) ethyl eicosapentanoate (XXIV), and
2-(4-docosahexanoyloxyphenyl) ethyl docosahexanoate (XXV).

12 more elements

Dependencies are inferred from the claim text.

Facts

Application: 10/406,792Filed 3 Apr 2003
Priority: ES 2002007723 Apr 2002
Published: US 2003/0225160 A14 Dec 2003
Granted: 29 Aug 2006
Term ends: Not estimatedThe source records don’t support an estimate.

Classification29 codes

A23C 9/13
Fermented milk preparations; Treatment using microorganisms or enzymes: using additives
A23C 9/152
Milk preparations; Milk powder or milk powder preparations: containing additives
A23C 15/12
Butter; Butter preparations; Making thereof: butter preparations
A23L 33/105
Using additives: plant extracts, their artificial duplicates or their derivatives