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US 7,094,946 B1Granted
Animal model for allergic disorders
AssigneeAstellas Pharma Inc.
InventorsTatsuya Sasakawa, Yasuyuki Higashi, Shozo Sakuma
Life of this patent
Estimating the term…
Abstract
An animal suitable as a model for an allergic disorder, wherein the animal is an immuno-modulated animal which has been sensitized with an antigen under a specific pathogen free environment such that when the animal displays allergy symptoms caused by the antigen.
Claims16
An NC/Nga mouse that has been sensitized with a mite extract by multiple sequential injections of mite antigen over a period 18 days or less in a pathogen-free environment,
- wherein said mouse exhibits at least one symptom of severe dermatitis in a shorter period of time than a conventional NC/Nga mouse;
- or
- wherein said mouse develops dermatitis lesions sufficiently severe for evaluating the effectiveness of a medicine by day 18.
Dependencies are inferred from the claim text.