Processes for preparing pesticidal intermediates
AssigneeBasf Agro B.V. Arnthem (NL) Wädenswil-Branch
InventorJean-Erick Ancel
Life of this patent
Estimating the term…
Abstract
The present invention relates to processes for the preparation of a compound of the formula wherein W is nitrogen or —CR3; R1 is halogen, haloalkyl, haloalkoxy, R4S(O)n— or —SF5; R2 is hydrogen or halogen; R3 is halogen; R4 is alkyl or haloalkyl; and n is 0, 1 or 2; and processes for using a compound of the formula (I) in the synthesis of compounds of the formula
Claims54
A process for the preparation of a compound of formula (X) or (XI):
- wherein R1 represents halogen, haloalkyl, haloalkoxy, —SF5, or R4S(O)n—, wherein R4 represents alkyl or haloalkyl, and n represents 0, 1 or 2;
- R2 represents hydrogen or halogen;
- and W represents CR3, wherein R3 represents halogen;
- which process comprises reacting a compound of formula (I):
- wherein R1, R2 and W are as defined above, with a source of hydrogen cyanide, to produce the corresponding compound of formula (VI):
- wherein R1, R2 and W are as defined above;
- followed by oxidizing the compound of formula (VI) thus obtained and optionally reacting it with a base.
A process for the preparation of a compound of formula (X) or (XI):
- wherein R represents halogen, haloalkyl, haloalkoxy, —SF5, or R4S(O)n—, wherein R4 represents alkyl or haloalkyl, and n represents 0, 1 or 2;
- R2 represents hydrogen or halogen;
- and W represents CR3, wherein R3 represents halogen;
- which process comprises reacting a compound of formula (I):
- wherein R1, R2 and W are as defined above, with hydrogen cyanide prepared from a metal cyanide salt in the presence of an acid, to produce the corresponding compound of formula (VI):
- wherein R1, R2 and W are as defined above;
- followed by oxidizing the compound of formula (VI) thus obtained and optionally reacting it with a base.
A process for the preparation of a compound of formula (X) or (XI):
- wherein R1 represents halogen, haloalkyl, haloalkoxy, —SF5, or R4S(O)n—, wherein R4 represents alkyl or haloalkyl, and n represents 0, 1 or 2;
- R2 represents hydrogen or halogen;
- and W represents CR3, wherein R3 represents halogen;
- which process comprises reacting a compound of formula (II):
- wherein R5 and R6 independently represent alkyl or together represent an alkylene chain having two or three carbon atoms, with an acid addition salt of an arylhydrazine compound of formula (III):
- wherein R1, R2 and W are as defined above, to produce the corresponding compound of formula (I):
- wherein R1, R2 and W are as defined above;
- followed by reacting the compound of formula (I) thus obtained with a source of hydrogen cyanide, to produce the corresponding compound of formula (VI):
- wherein R1, R2 and W are as defined above;
- followed by oxidizing the compound of formula (VI) thus obtained and optionally reacting it with a base.
A process for the preparation of a compound of formula (X) or (XI):
- wherein R1 represents halogen, haloalkyl, haloalkoxy, —SF5, or R4S(O)n—, wherein R4 represents alkyl or haloalkyl, and n represents 0, 1 or 2;
- R2 represents hydrogen or halogen;
- and W represents CR3, wherein R3 represents halogen;
- which process comprises reacting a compound of formula (IV):
- wherein R7 represents alkyl, with an arylhydrazine compound of formula (III):
- wherein R1, R2 and W are as defined above, to produce the corresponding compound of formula (I):
- wherein R1, R2 and W are as defined above;
- followed by reacting the compound of formula (I) thus obtained with a source of hydrogen cyanide, to produce the corresponding compound of formula (VI):
- wherein R1, R2 and W are as defined above;
- followed by oxidizing the compound of formula (VI) thus obtained and optionally reacting it with a base.
Dependencies are inferred from the claim text.