Back to results
US 7,094,806 B2Granted
7, 8 and 9-substituted tetracycline compounds
AssigneeTrustees of Tufts College
InventorsMark L. Nelson, Darrell J. Koza, Glen Rennie
Life of this patent
Estimating the term…
Abstract
7, 8 and 9-substituted tetracycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7, 8 and 9-substituted tetracycline compounds are described.
Claims12
A 7-, 8- or 9-substituted tetracycline compound of the formula:
- wherein:
- R4 and R4′ are each methyl;
- R5 is hydrogen or hydroxyl;
- R6 and R6′ are each independently hydrogen, methyl, or hydroxyl;
- R7 is furanyl;
- and
- R8 is hydrogen, phenyl, nitrophenyl, halo, or lower alkynyl;
- and R9 is hydrogen, amino, acetamide, or lower alkynyl;
- and pharmaceutically acceptable salts thereof.
6 more elements
Dependencies are inferred from the claim text.