5-HT2A receptor ligands

A compound of the formula I:

• wherein n is 0, 1, 2 or 3;
• W is CH2, CO, CHF or CH(OH);
• X is SO2, SO, CO or CH(OH);
• Y is CH2, CHF or CF2;
• Z is H, F or OH;
• Ar1 is phenyl or heteroaryl, wherein heteroaryl is selected from thiazole, imidazole and triazole, and wherein said phenyl or heteroaryl is unsubstituted or substituted with up to 3 substituents selected from halogen, CN, NO2, R1, OR2, COR2, CO2R2, OCOR1, SR2, S(O)tR1 where t is 1 or 2, N(R2)2, CON(R2)2, NR2COR1 and SO2N(R2)2;
• Ar2 is a mono- or bicyclic ring system selected from phenyl, naphthyl, pyrrole, oxazole, isoxazole, thiazole, isothiazole, and imidazole, and their benzo-fused and tetrahydrobenzo-fused derivatives, wherein said ring system is unsubstituted or substituted with up to 3 substituents selected from halogen, CN, NO2, R1 and OR2;
• R1 is C1-6alkyl or phenyl, which is unsubstituted or substituted with up to 5 fluorine substituents;
• and
• R2 is R1 or H;
• or two R2 groups attached to the same nitrogen atom may form a pyrrolidine, imidazole or triazole ring,
• or a pharmaceutically acceptable salt or hydrate thereof.