LTA4 hydrolase inhibitors

A compound corresponding to the following formula (I):

• in which
• X is NH2
• n1 and n3 are equal to 0 or 1, with (n1+n3) equal to 0 or 1
• n2 varies from 0 to 10
• Y is selected from the following groups:
• i) —O—
• R1 is selected from the following groups:
• i) a phenyl group which is unsubstituted or which is mono- or polysubstituted with substituents selected from halogen atoms and CF3, lower alkyl, lower alkoxy, NH2, NO2, CN, OH, CO2H, OPh, OCH2Ph, SCH3, SCH2CH3 and NHCOR6 groups
• Z is
• R2 and R3 are independently selected from the following groups:
• i) a hydrogen atom
• ii) a lower alkyl group
• iii) a lower alkyl group substituted with a halogen atom
• iv) a CF3 group
• v) a halogen atom;
• R6 represents a lower alkyl group;
• and
• R8 and R9 are independently selected from a hydrogen atom, a phenyl group, a lower alkyl group and a lower acetylthioalkylene group,
• as well as their diastereoisomers and enantiomers and their therapeutically acceptable salts.