Substituted fused heterocyclic C-glycosides

A compound of formula IV:

• wherein:
• one of the dashed lines between NR1 and X or between X and Y is present and if present such dashed lines represent a double bond, or alternatively both dashed lines are absent;
• two of V, M, and W are H and the third is
• R1 is H, or C1-4 alkyl;
• or, where the dashed line between NR1 and X is present, R1 is absent;
• X is N, C═O, CH, or C—Q—Z;
• Y is N—Q—Z or C—Q—Z, where X is N, C═O, or CH;
• Y is CH, where X is C—Q—Z;
• Q=—(CH2)n— where n=1 or 2;
• P=H, C1-7 acyl, or C1-6 alkoxycarbonyl;
• Z is substituted or unsubstituted, and is selected from C3-7 cycloalkyl, phenyl, a 5- or 6- membered heteroaryl having 1 or 2 heteroatoms independently selected from N, O, and S, a biaryl, a 9- or 10-membered fused bicyclyl, and a fused heterobicyclyl, wherein said fused heterobicyclyl has between 1 and 4 heteroatoms independently selected from N, O, and S;
• or a pharmaceutically acceptable salt, thereof.