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US 7,094,557 B2Granted
2-Methyl-3-butenyl-1-pyrophosphoric acid salt and agent for treating lymphocytes
AssigneeChugai Seiyaku Kabushiki Kaisha
InventorsYoshimasa Tanaka, Takehiko Uchiyama
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Abstract
A pharmaceutically acceptable salt of 2-methyl-3-butenyl-l-pyrophosphoric acid; an agent for treating lymphocytes which comprises at least one of 2-methyl-3-butenyl-l-pyrophosphoric acid, a pharmaceutically acceptable salt thereof, and a hydrate thereof; Vγ2Vδ2 type T cells treated by the same; and a medicine containing the same specifically stimulate and proliferate the human Vγ2Vδ2 type T cells, and also induce and enhance an antitumor activity thereof.
Claims3
A method for preparing activated lymphocytes which comprises:
- treating human Vγ2Vδ2 type T cells with a composition comprising at least one agent selected from the group consisting of:
- a) a pharmaceutically acceptable salt, or a hydrate, of 2-methyl-3-butenyl-1-pyrophosphoric acid, and
- b) 2-methyl-3-butenyl-1-pyrophosphoric acid so as to activated said T cells.
Dependencies are inferred from the claim text.