Diagnostic test kits
AssigneeUniversité Catholique De Louvain
InventorsJean-Paul Thomasi, Michel Gersdorff, Guy Rousseau
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Abstract
The invention provides a method for the treatment of prophylaxis of autoimmune inner ear disease, in particular, deafness caused by autoimmune inner ear disease, which comprises administering to a host in need thereof a vaccine comprising peripheral myelin protein zero. The invention further provides diagnostic methods and kits derived from the protein.
Claims4
A diagnostic test kit for diagnosing autoimmune inner ear disease, said diagnostic kit comprising:
- a polypeptide comprising SEQ ID NO:
- 1, attached to a solid substrate.
A diagnostic kit for diagnosing autoimmune inner ear disease, said diagnostic kit comprising:
- means for contacting a biological sample with a polypeptide comprising SEQ ID NO:
- 1 under conditions that allow for the formation of an antibody-antigen complex between the polypeptide and any antibodies presented in the biological sample, and
- means for detecting antibody-antigen complexes comprising said polypeptide, wherein formation of the antibody-antigen complex is indicative of the autoimmune inner ear disease of the subject.
A test for diagnosing autoimmune inner ear disease, said test comprising:
- a polypeptide comprising an antigenic determinant of the major peripheral myelin protein zero, attached to a solid substrate, and in contact with a tissue sample comprising antibodies, wherein said tissue sample is from a subject suffering from autoimmune inner ear diseases, wherein said polypeptide comprises SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.