Famotidine injections
AssigneeAstellas Pharma Inc.
InventorsKatsunori Nakata, Hiroshi Yatabe, Tsukasa Nishikawahara
Life of this patent
Estimating the term…
Abstract
The present invention exhibits a remarkable effect of making it possible to provide a famotidine injection solution containing famotidine at a high concentration, being stable for a long period of time at room temperature, and having a low viscosity without impairing the absorption of famotidine, which can be hardly provided so far.
Claims11
A famotidine injection solution containing famotidine or its salt in an amount of about 1 mg/ml to about 40 mg/ml in terms of the base, further containing one or two or more water-soluble acid amides selected from the group consisting of nicotinic acid amide, isonicotinic acid amide, gentisic acid ethanolamide, urea and N,N-dimethylacetamide in an amount of about 1 mg to about 30 mg per 1 mg of famotidine, and an acidic substance, and having a pH of about 5.5 to about 7.5 and a kinematic viscosity at room temperature of about 0.9 centistokes or more to about 3 centistokes or less.
Dependencies are inferred from the claim text.