Processes for manufacturing polymeric microspheres
AssigneeSciMed Life Systems, Inc.
InventorsMarcia Buiser, Samuel P. Baldwin
Life of this patent
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Abstract
Processes of manufacturing polymeric microspheres facilitate the generation of polymeric microspheres of size ranges smaller than 600 microns diameter by forming beads of a predetermined size from a starting material which may include a template polymer, and subsequently contacting the beads with a structural polymer. After crosslinking of the structural polymer has taken place, the template polymer may be removed to form the finished microspheres.
Claims57
A method for producing spherical polymeric particles, the method comprising the steps of:
- generating spherical beads of a desired size from a starting material comprising a template polymer;
- diffusing a structural polymer into the beads;
- and
- crosslinking the structural polymer, thereby producing polymeric spherical particles.
A method for producing spherical polymeric particles, the method comprising:
- generating spherical beads of a desired size from a starting material comprising a methacrylate template polymer;
- contacting the beads with a structural polymer;
- and
- crosslinking the structural polymer, thereby producing spherical polymeric particles.
A method for producing spherical polymeric particles comprising the steps of:
- generating ice beads;
- contacting the beads with a structural polymer;
- and
- crosslinking the structural polymer, thereby producing polymeric spherical particles.
A method, comprising:
- contacting a template polymer with a structural polymer to form a particle comprising the template polymer and the structural polymer;
- and
- removing at least a portion of the template polymer from the particle.
A method, comprising:
- contacting a first polymer with a second polymer to form a particle comprising the first and second polymers;
- and
- removing at least a portion of the first polymer from the particle,
- wherein the particle has a diameter of about 1000 microns or less.
Dependencies are inferred from the claim text.