Venezuelan equine encephalitis virus replicon encoding marburg virus proteins
AssigneeThe United States of America as represented by the Secretary of the Army
InventorsMichael C. Hevey, Diane L. Negley, Peter Pushko, Jonathan F. Smith, Alan L. Schmaljohn
Life of this patent
Estimating the term…
Abstract
Using the MBGV GP, NP, and virion proteins, a method and composition for use in inducing an immune response which is protective against infection with MBGV in nonhuman primates is described.
Claims6
Self replicating Venezuelan equine encephalitis virus replicon RNA encoding one or more Marburg virus (MIBGV) proteins selected from the group consisting of GP, NP, VP24, VP30, VP35, VP40 and GPΔTM.
A vaccine for MBGV comprising viral particles containing one or more Venezuelan equine encephalitis virus replicon RNA encoding one or more MBGV proteins selected from the group consisting of GP, NP, VP24, VP30, VP35, VP40 and GPΔTM.
Dependencies are inferred from the claim text.