Tissue lockable connecting structures

A method of providing a structurally supported bioconnection for a device, comprising the steps of:

• implanting a device having a perimeter with a plurality of outwardly extending tissue connectors mounted thereon through an opening in biological subject, each tissue connector defining an aperture sized in width at about 0.2–4 mm, wherein the tissue connectors have sufficient rigidity to be able to retain their shape and outwardly extending configuration in position in situ to thereby lock with local tissue, and wherein the tissue connectors are arranged on the device in a density of between about 10–200 per cm2;
• and
• growing proximately located tissue into proximately located tissue connectors such that the tissue connectors engage with the tissue to define a bioconnection which engages the device with localized tissue in a desired location in the subject.

A method of locking a foreign object into a biological subject, the foreign object comprising a plurality of outwardly extending tissue connectors connected to the outer perimeter thereof into a biological subject, each of the tissue connectors having an aperture formed therein, the method comprising the step of:

• implanting the object into a biological subject such that localized tissue grows into the apertures in the tissue connectors to provide structural support for the object in the biological subject, wherein the tissue connectors are sufficiently rigid so as to be able to substantially retain their shape and outwardly extending configuration in situ, wherein the apertures of the tissue connectors have an opening gap of between about 0.2 mm–5 mm, and wherein the object is adapted to reside in the biological subject for at least 6–12 months.

A method of locking a foreign object into a biological subject, the foreign object comprising a plurality of outwardly extending tissue connectors connected to the outer perimeter thereof into a biological subject, each of the tissue connectors having an aperture formed therein, the method comprising the step of:

• implanting the object into a biological subject such that localized tissue grows into the apertures in the tissue connectors to provide structural support for the object in the biological subject, wherein the apertures have an opening gap of between about 0.2 mm–5 mm, wherein the object is adapted to reside in the biological subject for at least 6–12 months, and wherein the tissue connectors are arranged on a portion of the perimeter of the object in a quantity of between about 50–100 per cm2.

A method of locking a foreign object into a biological subject, the foreign object comprising a plurality of outwardly extending tissue connectors connected to the outer perimeter thereof into a biological subject, each of the tissue connectors having an aperture formed therein, the method comprising the step of:

• implanting the object into a biological subject such that localized tissue grows into the apertures in the tissue connectors to provide structural support for the object in the biological subject, wherein the apertures have an opening gap of between about 0.2 mm–5 mm, wherein the object is adapted to reside in the biological subject for at least 6–12 months, and wherein the object is adapted to deliver insulin subcutaneously.

A method of locking a foreign object into a biological subject, the foreign object comprising a plurality of outwardly extending tissue connectors connected to the outer perimeter thereof into a biological subject, each of the tissue connectors having an aperture formed therein, the method comprising the step of:

• implanting the object into a biological subject such that localized tissue grows into the apertures in the tissue connectors to provide structural support for the object in the biological subject, wherein the apertures have an opening gap of between about 0.2 mm–5 mm, wherein the object is adapted to reside in the biological subject for at least 6–12 months, and wherein said object provides connections for peritoneal dialysis.

A method of locking a foreign object into a biological subject, the foreign object comprising a plurality of outwardly extending tissue connectors connected to the outer perimeter thereof into a biological subject, each of the tissue connectors having an aperture formed therein, the method comprising the step of:

• implanting the object into a biological subject such that localized tissue grows into the apertures in the tissue connectors to provide structural support for the object in the biological subject, wherein the apertures have an opening gap of between about 0.2 mm–5 mm, wherein the object is adapted to reside in the biological subject for at least 6–12 months, and wherein the tissue connectors are substantially rigid.

A method of locking a foreign object into a biological subject, the foreign object comprising a plurality of outwardly extending tissue connectors connected to the outer perimeter thereof into a biological subject, each of the tissue connectors having an aperture formed therein, the method comprising the step of:

• implanting the object into a biological subject such that localized tissue grows into the apertures in the tissue connectors to provide structural support for the object in the biological subject, wherein the apertures have an opening gap sized between about 0.2 mm–5 mm, wherein the object is adapted to reside in the biological subject for at least 6–12 months, and wherein the tissue connectors have sufficient rigidity to substantially retain their shape in situ.

A percutaneous access device configured for implantation into a subject to provide subcutaneous access therethrough, the device being characterized by a plurality of tissue lockable connecting structures having sufficient rigidity so as to be able to maintain a predetermined shape and orientation when external of the subject and when positioned in situ, at least some of the locked structures being located proximate to at least one selected external surface of the device to provide a skin level interface, the tissue lockable connecting structures defining respective air gap spaces sized from between about 0.2–4 mm.

A percutaneous access device configured for implantation into a subject to provide subcutaneous access therethrough, the device being characterized by a plurality of locked connecting structures located proximate at least one selected external surface thereof, the locked connecting structures defining an air gap space sized from between about 0.2–4 mm,

• wherein the device comprises a primary body with sidewalls defining an access passage therein, and wherein the locked connecting structures are a plurality of loops defining the gap spaces and extending outwardly from the primary body of the device.

A percutaneous access device configured for implantation into a subject to provide subcutaneous access therethrough, the device being characterized by

• a plurality of locked connecting structures located proximate to at least one selected external surface thereof, the locked connecting structures defining an air gap space sized from between about 0.2–4 mm,
• wherein the device comprises a primary body with sidewalk defining an access passage therein, and wherein the locked connecting structures are a plurality of hooks defining the gap spaces and extending outwardly from the primary body of the device.