Back to results
US 7,078,527 B2Granted
Method for producing halogenated 2-(3-butenylsulphanyl)-1,3-thiazoles
AssigneeBayer CropScience AG
InventorAlexander Straub
Life of this patent
Estimating the term…
Abstract
The present invention relates to a process for preparing compounds of the formula (I) where R is H or F, by (a) reacting a compound of the formula (II) where X is halogen, mesylate or tosylate with a thiocyanate, (b) reacting the resultant product with H2S or one of its salts to give a dithiocarbamate, and (c) reacting the dithiocarbamate with acetaldehyde, chloroacetaldehyde or an acetal thereof, and further relates to intermediates used in this process.
Claims13
A new process for preparing a compound of formula (I)
- where R is H or F,
- comprising
- (a) reacting a compount of formula (II)
- where
- R is H or F, and
- X is bromine, chlorine, mesylate, or tosylate, with a compound of formula (III)
- M+ SCN− (III)
- where M+ is hydrogen, an ammonium ion, a tetraalkylammonium ion, or
- an alkali metal or alkaline earth metal ion, optionally in the presence of a reaction auxiliary and optionally in the presence of a diluent, to give a compound of formula (IV)
- where R is H or F,
- (b) converting the compound of formula (IV) by adding hydrogen sulphide or salts thereof, optionally in the presence of a reaction auxiliary and optionally in the presence of diluent, to a compound of formula (V)
- where R is H or F,
- and
- (c) reacting the compound of formula (V) with acetaldehyde or choloroacetaldehyde (ClCH2CHO), or an acetal thereof, optionally in the presence of an acidic reaction auxiliary and optionally in the presence of a diluent, thereby forming the compound of formula (I).
11 more elements
Dependencies are inferred from the claim text.