Production of mammary secretion antibodies in farm animals
AssigneeMucoVax Holding B.V.
InventorSang He Lee
Life of this patent
Estimating the term…
Abstract
The present invention provides means and methods for obtaining an antibody in a mammary secretion product of a farm-animal comprising administering to said animal at least two compositions, which may be the same or different, comprising an antigen to which said antibody is to be raised, the method comprising administering at least a first of said compositions such that a high mucosal and/or systemic immune response is obtained and wherein at least a second of said compositions is administered to a mammary gland and/or a supramammary lymph node of said animal.
Claims6
Mature milk harvested after the colostrial stage from a farm-animal, the mature milk having a concentration of IgA specific for Clostridium difficile Toxin A of at least 0.5 μg/ml.
A milk product comprising a total immunoglobulin concentration normal for mature milk, and an IgA concentration specific for Clostridium difficile Toxin A of at least 0.5 μg/ml.
Dependencies are inferred from the claim text.