Immunotherapy of autoimmune disorders using antibodies which target B-cells
AssigneeImmunomedics, Inc.
InventorsDavid M. Goldenberg, Hans J. Hansen
Life of this patent
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Abstract
Antibodies that bind with a B-cell antigen provide an effective means to treat autoimmune disorders. Antibodies and fragments, which may be conjugated or naked, are used alone or in multimodal therapies. The antibodies may be bispecific antibodies which may be produced recombinantly as fusion proteins, or as hybrid, polyspecific antibodies.
Claims20
A method for treating an autoimmune disorder, comprising administering to a subject having an autoimmune disorder, an effective amount of a therapeutic composition comprising a pharmaceutically acceptable carrier and at least one non-blocking anti-CD22 antibody.
Dependencies are inferred from the claim text.