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US 7,071,382 B2Granted
Inhibitors of apoptosis proteins in plants
AssigneeE. I. Du Pont de Nemours and Company
InventorsRebecca E. Cahoon, Perry G. Caimi, Theodore M. Klein, Michele Morgante, Hajime Sakai, Jennie Bih-Jien Shen, Scott V. Tingey
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Abstract
This invention relates to an isolated nucleic acid fragment encoding an apoptosis inhibitory protein. The invention also relates to the construction of a chimeric gene encoding all or a portion of the apoptosis inhibitory protein, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the apoptosis inhibitory protein in a transformed host cell.
Claims12
An isolated polynucleotide comprising:
- (a) a nucleotide sequence encoding a polypeptide having DAD1 apoptosis inhibitor activity, wherein the amino acid sequence of the polypeptide and the amino acid sequence of SEQ ID NO:6 have at least 90% sequence identity, based on the Clustal alignment method with pairwise alignment default parameters of KTUPLE=1, GAP PENALTY=3, WINDOW=5 and DIAGONALS SAVED=5, or
- (b) the full-length complement of the nucleotide sequence of (a).
Dependencies are inferred from the claim text.