AMPA-binding human GluR4 receptors
AssigneeNPS Allelix Corp.
InventorsRajender Kamboj, Candace E. Elliott, Stephen L. Nutt
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Abstract
Described herein are isolated polynucleotides which code for an AMPA-type human CNS receptor, designated the human GluR4B receptor. The receptor is characterized structurally and the construction and use of cell lines expressing the receptor is disclosed.
Claims8
A human GluR4B receptor, in a form essentially free from other proteins of human origin.
An AMPA-binding fragment of the human GluR4B receptor.
An immunogenic fragment of a human GluR4B receptor that generates antibodies specific to a GluR4B receptor.
A human GluR4B receptor of SEQ ID NO. 2 in a form essentially free from other proteins of human origin.
A process for obtaining a substantially homogeneous source of a human EAA receptor which comprises the steps of culturing a cellular host transformed with a vector comprising a polynucleotide comprising nucleic acids arranged in a sequence that encodes the human GluR4B receptor, and then recovering the cultured cells.
Dependencies are inferred from the claim text.