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US 7,071,305 B2Granted
Isolated hOAT polypeptide
AssigneeGilead Sciences, Inc.
InventorTomas Cihlar
Life of this patent
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Abstract
This invention is concerned with human organic anion transporter (“hOAT”). Isolated nucleic acid encoding hOAT is provided, along with ioslated hOAT polypeptide. hOAT nucleic acid and/or hOAT polypeptide are employed in transgenic animals, recombinant cells, replicable vectors and analytical procedures for identifying hOAT agonists or antagonists, assays for identifying hOAT alleles and/or isotypes, screening tests for nephrotoxic or neurologically active compounds, and determination of drug-drug interactions within the kidney or brain.
Claims1
An isolated hOAT polypeptide having the sequence of SEQ. ID. NO. 2.
Dependencies are inferred from the claim text.