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US 7,071,300 B2Granted
IGF antagonist peptides
AssigneeGenentech, Inc.
InventorsKurt D. Deshayes, Henry B. Lowman, Michelle L. Schaffer, Sachdev S. Sidhu
Life of this patent
Estimating the term…
Abstract
Peptides are provided that antagonize the interaction of IGF-1 with its binding proteins, insulin receptor, and IGF receptor. These IGF antagonist peptides are useful in treating disorders involving IGF-1 as a causative agent, such as, for example, various cancers.
Claims3
A peptide comprising the sequence RNCFESVAALRRCMYG (SEQ ID NO:2), MDCLASVEALKWCMYG (SEQ ID NO:3), or FECLTSVEALRGCMYG (SEQ ID NO:4).
Dependencies are inferred from the claim text.