Anti-cancer compounds and methods related thereto
AssigneeThe Regents of the University of Colorado
InventorsJohn M. Stewart, Daniel C. F. Chan, Lajos Gera, Eunice York, Paul Bunn
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Abstract
The present invention provides compounds useful to inhibit tumor growth and to induce apoptosis. In general, the anti-cancer agents (ACA) are described by the formula: [ACA]n-X[Formula I] wherein X is a linker group having 2–5 functional groups or is absent, n=1, and ACA is selected from the group consisting of Formula II, Formula III, Formula IV, Formula V, and Formula VI, as described herein. Other compounds described herein are defined by the Formula VII, as described herein.
Claims4
The compound trans-3-(3-pyridyl)acryloyl-biphenylalanine-4-amino-2,2,6,6-tetramethylpiperidine (Pya-Bip-Atmp), or a pharmaceutically acceptable salt thereof.
A method of inhibiting the growth of a tumor cell comprising contacting said tumor cell with the compound trans-3-(3-pyridyl)acryloyl-biphenylalanine-4-amino-2,2,6,6-tetramethylpiperidine (Pya-Bip-Atmp), or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.